Reporter
Part:BBa_K5319674:Design
Designed by: YuFei Xie Group: iGEM24_ZJU-China (2024-09-30)
pJUMP42x-2a-TRS/RS-sfGFP
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 10
Illegal NheI site found at 33 - 21INCOMPATIBLE WITH RFC[21]Illegal XhoI site found at 101
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI.rc site found at 147
Design Notes
The 14-nt recruiting sequence is modified from the sequence in "Hydrolytic endonucleolytic ribozyme (HYER)is programmable for sequence-specific DNA cleavage" corresponding to the loxp site we want it to recognize.
Source
HYER(hydrolytic endonucleolytic ribozymes), identified from group II-C introns in public bacterial genome database in the article "Hydrolytic endonucleolytic ribozyme (HYER)is programmable for sequence-specific DNA cleavage".